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CONCLUSIONS: In adult ventricular myocytes, KCNE1 maintains a stable presence on the cell surface, whereas KCNQ1 is dynamic in its localization. KCNQ1 is largely in an intracellular reservoir under basal conditions but can traffic to the cell surface and boost the Cited by: An in vitro model system of cultured adult murine ventricular myocytes was developed to facilitate investigation of cell-mediated myocyte injury. Isolated adult myocytes were incubated with either HICs or MLR effector cells, and myocyte death was quantified by counting the number of rod-shaped myocytes excluding trypan by:

Cocultures of adult ventricular myocytes with stellate ganglia or intrinsic cardiac neurones from guinea pigs: spontaneous activity and pharmacological properties. Horackova M (1), Huang MH, Armour JA, Hopkins DA, Mapplebeck by: Cytochrome P 2J2 isoform (CYP2J2) is a drug-metabolizing enzyme that is highly expressed in adult ventricular myocytes. It is responsible for the bioactivation of arachidonic acid (AA) into epoxyeicosatrienoic acids (EETs).Cited by: 5.

Adult LV myocytes and neonatal ventricular myocytes were fixed for 30 min in 4% paraformaldehyde in PBS-E. After 2 rinses with PBS-E, myocytes were permeabilized for 2 min with % Triton X Myocytes were rinsed 2x with PBS-E, and once with BLOTTO (5% nonfat dry milk, M NaCl, and 50 mM; pH ).Cited by: